Hemant Suryawanshi, PhD
- Assistant Professor of Reproductive Sciences (in Obstetrics and Gynecology) at CUMC
Overview
Academic Appointments
- Assistant Professor of Reproductive Sciences (in Obstetrics and Gynecology) at CUMC
Credentials & Experience
Education & Training
- BSc, 2006 Microbiology, Shivaji University, India
- MSc, 2008 Microbiology, University of Pune, India
- PhD, 2015 Biotechnology, Institute of Genomics and Integrative Biology, New Delhi, India
- Fellowship: 2012 Rockefeller University, New York, NY
- Fellowship: 2013 Institute of Genomics and Integrative Biology, New Delhi, India
Research
As a postdoctoral researcher in Prof. Thomas Tuschl’s lab at Rockefeller University, he applied single-cell approaches to explore the transcriptomic landscape of diverse human tissues, including fetal heart, adult skin, kidney, placenta, decidua, and testis, in the context of diseases such as lupus nephritis, atopic dermatitis, transplantation, and congenital heart block.
As a faculty member, Dr. Suryawanshi’s research focuses on developing innovative technologies to address clinical challenges, with a primary emphasis on reproductive diseases. His work integrates microfluidics, single-cell analysis, and computer vision to create novel tools for analyzing complex biological systems, with the goal of improving diagnostics, treatment strategies, and personalized care in reproductive health.
Research Interests
- Computer Vision
- Male Infertility
- Microfluidics
- Preeclampsia
- Single-cell Biology
- Transcriptomics
Selected Publications
- Suryawanshi H, Morozov P, Straus A, Sahasrabudhe N, Max KEA, Garzia A, Kustagi M, Tuschl T, Williams Z. A single-cell survey of the human first-trimester placenta and decidua. Science Advances. 2018 Oct 31;4(10):eaau4788.
- Der E*, Suryawanshi H*, Morozov P, Kustagi M, Goilav B, Ranabothu S, Izmirly P, Clancy R, Belmont HM, Koenigsberg M, Mokrzycki M, Rominieki H, Graham JA, Rocca JP, Bornkamp N, Jordan N, Schulte E, Wu M, Pullman J, Slowikowski K, Raychaudhuri S, Guthridge J, James J, Buyon J, Tuschl T, Putterman C; Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium. Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. Nature Immunology. 2019 Jul;20(7):915-927.
- Suryawanshi H, Clancy R, Morozov P, Halushka MK, Buyon JP, Tuschl T. Cell atlas of the foetal human heart and implications for autoimmune-mediated congenital heart block. Cardiovascular research. 2020 Jul 1;116(8):1446-1457.
- Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, Garzia A, Morozov P, Manickavel S, McFarland HL, Roeder RG, Hafner M, Tuschl T. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. 2017 Mar 23;543(7646):568-572.
- He H*, Suryawanshi H*†, Morozov P, Gay-Mimbrera J, Del Duca E, Kim HJ, Kameyama N, Estrada Y, Der E, Krueger JG, Ruano J, Tuschl T†, Guttman-Yassky E†. Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. Journal of Allergy and Clinical Immunology. 2020 Jun;145(6):1615-1628.
- Suryawanshi H†, Yang H, Lubetzky M, Morozov P, Lagman M, Alonso A, Li C, Snopkowski C, Mueller FB, Lee JR, Dadhania DM, Salvatore SP, Seshan SV, Sharma VK, Suthanthiran M, Tuschl T†, Muthukumar T†. Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts. PLOS One. 2022 17(6): e0267704.
* Authors contributed equally (co-first-authors)
† Co-corresponding-authors
For a complete list of publications, please visit PubMed.gov(link is external and opens in a new window)